Publications '15 - '18
79. Li, D., Dulloo, I., & Sabapathy, K. (2018). Context-dependent AMPK activation distinctly regulates TAp73 stability and transcriptional activity. Signal Transduction and Targeted Therapy, 3, 20. https://doi.org/10.1038/s41392-018-0020-y
78. Hwang, L. A., Phang, B. H., Liew, O. W., Iqbal, J., Koh, X. H., Koh, X. Y., Othman, R., Xue, Y., Richards, A. M., Lane, D. P., & Sabapathy, K. (2018). Monoclonal Antibodies against Specific p53 Hotspot Mutants as Potential Tools for Precision Medicine. Cell Reports, 22(1), 299-312.
https://doi.org/10.1016/j.celrep.2017.11.112
77. Huang, M. N., Yu, W., Teoh, W. W., Ardin, M., Jusakul, A., Ng, A., Boot, A., Abedi-Ardekani, B., Villar, S., Myint, S. S., Othman, R., Poon, S. L., Heguy, A., Olivier, M., Hollstein, M., Tan, P., Teh, B. T., Sabapathy, K., Zavadil, J., & Rozen, S. G. (2017). Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors. Genome Research, 27(9), 1475–1486. https://doi.org/10.1101/gr.220038.116
76. Sabapathy, K., & Lane, D. P. (2018). Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others. Nature Reviews Clinical Oncology, 15(1), 13–30. https://doi.org/10.1038/nrclinonc.2017.151
75. Wang, C., McPherson, J. R., Zhang, L. H., Rozen, S., & Sabapathy, K. (2016). Transcription-associated mutation of lasR in Pseudomonas aeruginosa. DNA Repair, 46, 9–19. https://doi.org/10.1016/j.dnarep.2016.09.001
74. Tan, C. T., Zhou, Q. L., Su, Y. C., Fu, N. Y., Chang, H. C., Tao, R. N., Sukumaran, S. K., Baksh, S., Tan, Y. J., Sabapathy, K., Yu, C. D., & Yu, V. C. (2016). MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria. Cell Reports, 16(1), 174–185.
https://doi.org/10.1016/j.celrep.2016.05.068
73. Yaligar, J., Teoh, W. W., Othman, R., Verma, S. K., Phang, B. H., Lee, S. S., Wang, W. W., Toh, H. C., Gopalan, V., Sabapathy, K., & Velan, S. S. (2016). Longitudinal metabolic imaging of hepatocellular carcinoma in transgenic mouse models identifies acylcarnitine as a potential biomarker for early detection. Scientific Reports, 6, 20299. https://doi.org/10.1038/srep20299
72. Sabapathy K. (2015). p73: a Positive or Negative Regulator of Angiogenesis, or Both?. Molecular and Cellular Biology, 36(6), 848–854. https://doi.org/10.1128/MCB.00929-15
71. Sabapathy K. (2015). The Contrived Mutant p53 Oncogene - Beyond Loss of Functions. Frontiers In Oncology, 5, 276. https://doi.org/10.3389/fonc.2015.00276
70. Phang, B. H., Othman, R., Bougeard, G., Chia, R. H., Frebourg, T., Tang, C. L., Cheah, P. Y., & Sabapathy, K. (2015). Amino-terminal p53 mutations lead to xpression of apoptosis proficient p47 and prognosticate better survival, but predispose to tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America, 112(46), E6349–E6358. https://doi.org/10.1073/pnas.1510043112
69. Dulloo, I., Hooi, P. B., & Sabapathy, K. (2015). Hypoxia-induced DNp73 stabilization regulates Vegf-A expression and tumor angiogenesis similar to TAp73. Cell Cycle, 14(22), 3533–3539. https://doi.org/10.1080/15384101.2015.1078038
68. Subramanian, D., Bunjobpol, W., & Sabapathy, K. (2015). Interplay between TAp73 Protein and Selected Activator Protein-1 (AP-1) Family Members Promotes AP-1 Target Gene Activation and Cellular Growth. The Journal of Biological Chemistry, 290(30), 18636–18649.
https://doi.org/10.1074/jbc.M115.636548
67. Teoh, W. W., Xie, M., Vijayaraghavan, A., Yaligar, J., Tong, W. M., Goh, L. K., & Sabapathy, K. (2015). Molecular characterization of hepatocarcinogenesis using mouse models. Disease Models & Mechanisms, 8(7), 743–753. https://doi.org/10.1242/dmm.017624
66. Dulloo, I., Phang, B. H., Othman, R., Tan, S. Y., Vijayaraghavan, A., Goh, L. K., Martin-Lopez, M., Marques, M. M., Li, C. W., Wang, d., Marín, M. C., Xian, W., McKeon, F., & Sabapathy, K. (2015). Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Nature Cell Biology, 17(4), 511–523. https://doi.org/10.1038/ncb3130