Publications '07 - '10

50. Toh, W. H., Nam, S. Y., & Sabapathy, K. (2010). An essential role for p73 in regulating mitotic cell death. Cell Death and Differentiation, 17(5), 787–800.

49. Gough, D. J., Messina, N. L., Hii, L., Gould, J. A., Sabapathy, K., Robertson, A. P., Trapani, J. A., Levy, D. E., Hertzog, P. J., Clarke, C. J., & Johnstone, R. W.(2010). Functional crosstalk between type I and II interferon through the regulated expression of STAT1. PLoS Biology, 8(4), e1000361.

48. Song, J. Y., Han, H. S., Sabapathy, K., Lee, B. M., Yu, E., & Choi, J. (2010). Expression of a homeostatic regulator, Wip1 (wild-type p53 - induced phosphatase), is temporally induced by c-Jun and p53 in response to UV irradiation. The Journal of Biological Chemistry, 285(12), 9067–9076.

47. Dulloo, I., Gopalan, G., Melino, G., & Sabapathy, K. (2010). The antiapoptotic DeltaNp73 is degraded in a c-Jun-dependent manner upon genotoxic stress through the antizyme-mediated pathway. Proceedings of the National Academy of Sciences of the United States of America, 107(11), 4902–4907.

46. Chua, H. W., Ng, D., Choo, S., Lum, S. S., Li, H., Soh, L. Y., Sabapathy, K., & Seow, A. (2010). Effect of MDM2 SNP309 and p53 codon 72 polymorphisms on lung cancer risk and survival among non-smoking Chinese women in Singapore. BMC Cancer, 10, 88.

45. Xie, M., & Sabapathy, K. (2010). Tyrosine 170 is dispensable for c-Jun turnover. Cellular Signalling, 22(2), 330–337.

44. Baum, N., Schiene-Fischer, C., Frost, M., Schumann, M., Sabapathy, K., Ohlenschläger, O., Grosse, F., & Schlott, B. (2009). The prolyl cis/trans isomerase cyclophilin 18 interacts with the tumor suppressor p53 and modifies its functions in cell cycle regulation and apoptosis. Oncogene, 28(44), 3915–3925.

43. Shin, S., Asano, T., Yao, Y., Zhang, R., Claret, F. X., Korc, M., Sabapathy, K., Menter, D. G., Abbruzzese, J. L., & Reddy, S. (2009). Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism. Molecular Cancer Research, 7(5), 745–754.

42. Sabapathy, K., & Nam, S. Y. (2008). Defective MHC class I antigen surface expression promotes cellular survival through elevated ER stress and modulation of p53 function. Cell Death and Differentiation, 15(9), 1364–1374.

41. Toh, W. H., Logette, E., Corcos, L., & Sabapathy, K. (2008). TAp73beta and DNp73beta activate the expression of the pro-survival caspase-2S. Nucleic Acids Research, 36(13), 4498–4509.

40. Lee, M. K., & Sabapathy, K. (2008). The R246S hot-spot p53 mutant exerts dominant-negative effects in embryonic stem cells in vitro and in vivo. Journal of Cell Science, 121(11), 1899–1906.

39. Kolomeichuk, S. N., Terrano, D. T., Lyle, C. S., Sabapathy, K., & Chambers, T. C. (2008). Distinct signaling pathways of microtubule inhibitors--vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively. The FEBS Journal, 275(8), 1889–1899.

38. Lum, S. S., Chua, H. W., Li, H., Li, W. F., Rao, N., Wei, J., Shao, Z., & Sabapathy, K. (2008). MDM2 SNP309 G allele increases risk but the T allele is associated with earlier onset age of sporadic breast cancers in the Chinese population. Carcinogenesis, 29(4), 754–761.

37. Phang, B. H., Linn, Y. C., Li, H., & Sabapathy, K. (2008). MDM2 SNP309 G allele decreases risk but does not affect onset age or survival of Chinese leukaemia patients. European Journal of Cancer, 44(5), 760–766.

36. Nam, S. Y., Lee, M. K., & Sabapathy, K. (2008). The tumour-suppressor p53 is not required for pancreatic beta cell death during diabetes and upon irradiation. The Journal of Physiology, 586(2), 407–417.

35. Lee, M. K., & Sabapathy, K. (2007). Phosphorylation at carboxyl-terminal S373 and S375 residues and 14-3-3 binding are not required for mouse p53 function. Neoplasia, 9(9), 690–698.

34. Vikhanskaya, F., Toh, W. H., Dulloo, I., Wu, Q., Boominathan, L., Ng, H. H., Vousden, K. H., & Sabapathy, K. (2007). p73 supports cellular growth through c-Jun- dependent AP-1 transactivation. Nature Cell Biology, 9(6), 698–705.

33. Phang, B. H., & Sabapathy, K. (2007). The codon 72 polymorphism-specific effects of human p53 are absent in mouse cells: implications on generation of mouse models. Oncogene, 26(21), 2964–2974.

32. Vikhanskaya, F., Lee, M. K., Mazzoletti, M., Broggini, M., & Sabapathy, K. (2007). Cancer-derived p53 mutants suppress p53-target gene expression—potential mechanism for gain of function of mutant p53. Nucleic Acids Research, 35(6), 2093–2104.

31. Hettinger, K., Vikhanskaya, F., Poh, M. K., Lee, M. K., de Belle, I., Zhang, J. T., Reddy, S. A., & Sabapathy, K. (2007). c-Jun promotes cellular survival by suppression of PTEN. Cell Death and Differentiation, 14(2), 218–229.

30. Li, X. M., Li, C. C., Yu, S. S., Chen, J. T., Sabapathy, K., & Ruan, D. Y. (2007). JNK1 contributes to metabotropic glutamate receptor-dependent long-term depression and short-term synaptic plasticity in the mice area hippocampal CA1. The European Journal of Neuroscience, 25(2), 391–396.

29. Gough, D. J., Sabapathy, K., Ko, E. Y., Arthur, H. A., Schreiber, R. D., Trapani, J. A., Clarke, C. J., & Johnstone, R. W. (2007). A novel c-Jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon gamma response genes. The Journal of Biological Chemistry, 282(2), 938–946.